LFU:online

Die Studierenden können ein umfassendes Verständnis über die molekularen und zellulären Faktoren der zellulären Seneszenz sowie deren beim Alterungsprozess darlegen. 

Introduction to the concept and hallmarks of cellular senescence. Molecular and cellular mechanisms underlying the induction, maintenance, and heterogeneity of senescent states. Experimental models to study replicative and stress-induced senescence in human cells. Physiological roles of senescence in development and tissue homeostasis. Contribution of senescence to organismal aging and age-related pathologies. Emerging therapeutic strategies targeting senescent cells for the prevention and treatment of age-associated diseases.

Written exam