740107 Modern methods of active ingredient research
winter semester 2017/2018 | Last update: 17.01.2022 | Place course on memo listDrug research in the pharmaceutical industry today is in many qspects quite different from what it used to be only fifteen years ago. In this course the students will be introduced to the modern aspects of basic drug discovery in the preclinical setting.
Methods nowadays used in the drug discovery including:
1. Target identification and target validation
2. Lead identification and optimization:
- Drug discovery from natural sources (e.g. plants, marine organisms, microbes, and animal sources)
- Applied synthetic methods (e.g. combinatorial synthesis, solid phase synthesis)
- Parallel synthesis (lead optimization)
3. Toxicological aspects during drug development
-Reactive drug metabolites
- Blocage of the hERG K+ receptor in the heart
Lecture (power-point presentation)
written examination
Will be discussed in the first lesson.
Subject to modification.
- Faculty of Chemistry and Pharmacy
Group 0
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Date | Time | Location | ||
Thu 2017-12-07
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10.30 - 12.00 | PMS101 PMS101 | ||
Thu 2017-12-14
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10.30 - 12.00 | PMS101 PMS101 | ||
Thu 2018-01-11
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10.30 - 12.00 | PMS101 PMS101 | ||
Thu 2018-01-18
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10.30 - 12.00 | PMS101 PMS101 | ||
Mon 2018-01-22
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13.15 - 14.30 | L.EG.220 L.EG.220 | ||
Thu 2018-01-25
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10.30 - 12.00 | PMS101 PMS101 | ||
Wed 2018-01-31
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10.45 - 12.15 | L.EG.220 L.EG.220 | ||
Fri 2018-04-06
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10.00 - 12.00 | PMS101 PMS101 | Prüfung |