740107 Modern methods of active ingredient research

winter semester 2017/2018 | Last update: 17.01.2022 Place course on memo list
740107
Modern methods of active ingredient research
VO 1
2
Block
not applicable
German

Drug research in the pharmaceutical industry today is in many qspects quite different from what it used to be only fifteen years ago. In this course the students will be introduced to the modern aspects of basic drug discovery in the preclinical setting.

Methods nowadays used in the drug discovery including: 

1. Target identification and target validation

2. Lead identification and optimization:

- Drug discovery from natural sources (e.g. plants, marine organisms, microbes, and animal sources)

- Applied synthetic methods (e.g. combinatorial synthesis, solid phase synthesis)

- Parallel synthesis (lead optimization)

3. Toxicological aspects during drug development

-Reactive drug metabolites

- Blocage of the hERG K+ receptor in the heart

 

Lecture (power-point presentation)

written examination

Will be discussed in the first lesson.

not applicable

Subject to modification.

07.12.2017
Group 0
Date Time Location
Thu 2017-12-07
10.30 - 12.00 PMS101 PMS101
Thu 2017-12-14
10.30 - 12.00 PMS101 PMS101
Thu 2018-01-11
10.30 - 12.00 PMS101 PMS101
Thu 2018-01-18
10.30 - 12.00 PMS101 PMS101
Mon 2018-01-22
13.15 - 14.30 L.EG.220 L.EG.220
Thu 2018-01-25
10.30 - 12.00 PMS101 PMS101
Wed 2018-01-31
10.45 - 12.15 L.EG.220 L.EG.220
Fri 2018-04-06
10.00 - 12.00 PMS101 PMS101 Prüfung