740450 Basic principles of drug action

summer semester 2018 | Last update: 06.11.2019 Place course on memo list
740450
Basic principles of drug action
VO 2
4
Block
annually
German

In this course students will gain insight into the basic principles of drug effects determined by the interaction between drugs and the organism. This includes the effects and mechanisms of drugs in the organism itself (pharmacodynamics) and the time-dependent changes in drug concentrations by the organism (pharmacokinetics). This knowledge is the prerequisite for clinical pharmacotherapy.

Pharmacodanymics:

  • Mode of action of drugs including molecular structures and intracellular signaling cascades
  • Qualitative aspects of drug actions
  • Dose-response relationship

Pharmacokinetics:

  • Pharmacokinetic  processes (the LADME system)
  • Pharmacokinetic parameters
  • Compartment models

Pharmacogenetics:

  • Explaining the risks of individual differences in drug responses determined by genetic variants of proteins controlling pharmacodynamic or pharmacokinetic processes.

computer-aided visualized presentations, online handouts.

Written exam (MC and short answers)

Recommended books for further reading are :

  • Mutschler, Geisslinger, Kroemer, Ruth, Schäfer-Korting Mutschler Arzneimittelwirkungen: Lehrbuch der Pharmakologie und Toxikologie (Teil A - Allgemeiner Teil)
  • Aktories, Förstermann, Hofmann, Starke Allgemeine und spezielle Pharmakologie und Toxikologie (Kapitel „Allgemeine Pharmakologie und Toxikologie)
  • Rang, Dale: Rang and Dales’s Pharmacology (Section 1)

The successful completion of modules 4 and 7 is prerequisite for this course.

not applicable

Subject to change.

07.03.2018
Group 0
Date Time Location
Wed 2018-03-07
14.00 - 16.00 M.EG.180 M.EG.180
Fri 2018-03-09
11.45 - 13.45 L.EG.220 L.EG.220
Wed 2018-03-14
14.00 - 16.00 M.EG.180 M.EG.180
Fri 2018-03-16
11.45 - 13.45 L.EG.220 L.EG.220
Wed 2018-03-21
14.00 - 16.00 M.EG.180 M.EG.180
Fri 2018-03-23
11.45 - 13.45 L.EG.220 L.EG.220
Wed 2018-04-11
14.00 - 16.00 M.EG.180 M.EG.180
Wed 2018-04-18
14.00 - 16.00 M.EG.180 M.EG.180
Fri 2018-04-20
11.45 - 13.45 L.EG.220 L.EG.220
Wed 2018-04-25
14.00 - 16.00 M.EG.180 M.EG.180
Fri 2018-04-27
11.45 - 13.45 L.EG.220 L.EG.220
Wed 2018-05-02
14.00 - 16.00 M.EG.180 M.EG.180
Mon 2018-07-02
10.30 - 12.30 M.EG.180/L.EG.200 M.EG.180/L.EG.200 Prüfungstermin
Wed 2018-09-26
10.30 - 12.30 M.EG.180/L.EG.200 M.EG.180/L.EG.200 Prüfungstermin