LFU:online

Einfluss moderner Genomsequenzierungsmethoden auf die Humangenetik; ethische und soziale Aspekte.

1. Sequencing history, techniques, and whole genome, exome approaches. The Human Genome.
2. Mutation rates in males and females; recombination; germ cells vs. somatic cells; telomeres; effects on ageing.
3. Human Evolution: Genetics and  Paläoanthropology,  Out of Africa Hypothesis, Neanderthals and other Archaic humans; Adaptation, skin colour and other markers.
4. “Precision Medicine”: WES and WGS vs. GWAS; successes and failures; mutation rate in normal and cancer cells. Consequences of the Crspr/Cas technology on human choices.
5. Epigenetics: From development to differentiation of somatic cells, X-chromosome inactivation to genomic Imprinting

Vorlesung und Seminarvorträge.

Mündlich

Wird gesondert bekanntgegeben.

Anmeldereihung:

1. Studenten im DP AGE_REG, dann andere Doktoratsstudenten
2. Studenten im Masterstudium MOLZEB, dann andere Masterstudenten